Pattern and timing of the coronary sinus activation to guide rapid diagnosis of atrial tachycardia after atrial fibrillation ablation

Pascale, Patrizio; Shah, Ashok J; Roten, Laurent; Scherr, Daniel; Komatsu, Yuki; Jadidi, Amir S; Ramoul, Khaled; Daly, Matthew; Denis, Arnaud; Wilton, Stephen B; Derval, Nicolas; Sacher, Frédéric; Hocini, Mélèze; Haïssaguerre, Michel; Jaïs, Pierre (2013). Pattern and timing of the coronary sinus activation to guide rapid diagnosis of atrial tachycardia after atrial fibrillation ablation. Circulation - arrhythmia and electrophysiology, 6(3), pp. 481-90. Lippincott Williams & Wilkins 10.1161/CIRCEP.113.000182

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BACKGROUND

Atrial tachycardias (AT) during or after ablation of atrial fibrillation frequently pose a diagnostic challenge. We hypothesized that both the patterns and the timing of coronary sinus (CS) activation could facilitate AT mapping.

METHODS AND RESULTS

A total of 140 consecutive postpersistent atrial fibrillation ablation patients with sustained AT were investigated by conventional mapping. CS activation pattern was defined as chevron or reverse chevron when the activations recorded on both the proximal and the distal CS dipoles were latest or earliest, respectively. The local activation of mid-CS was timed with reference to Ppeak-Ppeak (P-P) interval in lead V1. A ratio, mid-CS activation time to AT cycle length, was computed. Of 223 diagnosed ATs, 124 were macroreentrant (56%) and 99 were centrifugal (44%). When CS activation was chevron/reverse chevron (n=44; 20%), macroreentries were mostly roof dependent. With reference to P-P interval, mid-CS activation timing showed specific consistency for peritricuspid and perimitral AT. Proximal to distal CS activation pattern and mid-CS activation at 50% to 70% of the P-P interval (n=30; 13%) diagnosed peritricuspid AT with 81% sensitivity and 89% specificity. Distal to proximal CS activation and mid-CS activation at 10% to 40% of the P-P interval (n=44; 20%) diagnosed perimitral AT with 88% sensitivity and 75% specificity.

CONCLUSIONS

The analysis of the patterns and timing of CS activation provides a rapid stratification of most likely macroreentrant ATs and points toward the likely origin of centrifugal ATs. It can be included in a stepwise diagnostic approach to rapidly select the most critical mapping maneuvers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Roten, Laurent

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1941-3149

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Laurent Roten

Date Deposited:

25 Feb 2014 10:38

Last Modified:

13 Jul 2015 14:42

Publisher DOI:

10.1161/CIRCEP.113.000182

PubMed ID:

23629735

Uncontrolled Keywords:

ablation, atrial fibrillation, atrial flutter, atrial tachycardia, coronary sinus, electrophysiology mapping, mapping

URI:

https://boris.unibe.ch/id/eprint/42250

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