The effect of GH replacement therapy on different fat compartments: a whole-body magnetic resonance imaging study

Egger, Andrea; Buehler, Tania; Boesch, Chris; Diem, Peter; Stettler, Christoph; Christ, Emanuel R (2011). The effect of GH replacement therapy on different fat compartments: a whole-body magnetic resonance imaging study. European journal of endocrinology, 164(1), pp. 23-9. Bristol: BioScientifica Ltd. 10.1530/EJE-10-0702

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Patients with GH deficiency (GHD) are insulin resistant with an increase in visceral fat mass (FM). Whether this holds true when sedentary control subjects (CS) are matched for waist has not been documented. GH replacement therapy (GHRT) results in a decrease in FM. Whether the decrease in FM is mainly related to a reduction in visceral FM remains to be proven. The aim was to separately assess visceral and subcutaneous FM in relation to insulin resistance (IR) in GHD patients before and after GHRT and in sedentary CS.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology > DCR Magnetic Resonance Spectroscopy and Methodology (AMSM)
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Bühler, Tania; Bösch, Christoph Hans; Diem, Peter; Stettler, Christoph and Christ, Emanuel

ISSN:

0804-4643

Publisher:

BioScientifica Ltd.

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

06 Dec 2013 13:19

Publisher DOI:

10.1530/EJE-10-0702

PubMed ID:

20930061

Web of Science ID:

000285633000004

URI:

https://boris.unibe.ch/id/eprint/423 (FactScience: 198783)

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