The role of postoperative antibiotics in facial fractures: Comparing the efficacy of a 1-day versus a prolonged regimen

Mottini, Matthias; Wolf, Renzo; Soong, Poh Luon; Lieger, Olivier; Nakahara, Ken; Schaller, Benoît (2014). The role of postoperative antibiotics in facial fractures: Comparing the efficacy of a 1-day versus a prolonged regimen. Journal of Trauma and Acute Care Surgery, 76(3), pp. 720-724. Lippincott Williams & Wilkins 10.1097/TA.0000000000000123

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BACKGROUND The goal of this study was to evaluate the influence of the duration of postoperative antibiotics (1 day vs. ≥ 5 days) on wound infections following surgical treatment of facial fractures. METHODS Three hundred thirty-nine patient case histories with a total of 498 fractures were reviewed retrospectively with regard to infections occurring within a 6-month period following surgical management. Patients were divided into two groups based on the duration of postoperative antibiotics administered. Group A consisted of 125 patients who had 1 day of postoperative antibiotics, whereas Group B consisted of 214 patients who had five or more days of postoperative antibiotics. Statistical analysis was conducted to assess for possible differences in the rate of postoperative infections. RESULTS Five patients in Group A (4%) and seven patients in Group B (3.27%) developed infections within the follow-up period. Of these 12 patients, seven had sustained multiple facial bone fractures. Eleven infections occurred in patients with mandibular fractures and one in a midfacial fracture. Statistical analysis using Fisher's exact test showed no significant difference (p = 0.77) in the incidence of infection between Groups A and B. CONCLUSION In this retrospective study, the use of prolonged postoperative antibiotics in uncomplicated mandibular and midfacial fractures had no significant benefit in reducing the incidence of infections. LEVEL OF EVIDENCE Therapeutic study, level IV.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Schädel-, Kiefer- und Gesichtschirurgie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Schädel-, Kiefer- und Gesichtschirurgie

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Mottini, Matthias; Lieger, Olivier; Nakahara, Ken and Schaller, Benoît

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2163-0755

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Caroline Dominique Zürcher

Date Deposited:

07 Mar 2014 03:52

Last Modified:

22 Oct 2015 14:00

Publisher DOI:

10.1097/TA.0000000000000123

PubMed ID:

24553540

BORIS DOI:

10.7892/boris.42653

URI:

https://boris.unibe.ch/id/eprint/42653

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