Evangelopoulos, D. S.; Stathopoulos, I. P.; Morassi, G. P.; Koufos, S.; Albarni, A.; Karampinas, P. K.; Stylianakis, A.; Kohl, Sandro; Pneumaticos, S.; Vlamis, J. (2013). Sonication: a valuable technique for diagnosis and treatment of periprosthetic joint infections. Scientific world journal, 2013, p. 375140. Hindawi Publishing Corporation 10.1155/2013/375140
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BACKGROUND
Periprosthetic joint infection (PJI) is the most severe complication, following joint arthroplasty. Identification of the causal microbial factor is of paramount importance for the successful treatment.
PURPOSE
The aim of this study is to compare the sonication fluid cultures derived from joint prosthetic components with the respective periprosthetic tissue cultures.
METHODS
Explanted prosthesis components for suspected infection were placed into a tank containing sterile Ringer's solution and sonicated for 1 minute at 40 kHz. Sonication fluid cultures were examined for 10 days, and the number and identity of any colony morphology was recorded. In addition, periprosthetic tissue specimens (>5) were collected and cultured according to standard practice. The duration of antimicrobial interruption interval before culture sampling was recorded.
RESULTS
Thirty-four patients composed the study group. Sonication fluid cultures were positive in 24 patients (70.5%). Sixteen of thirty four periprosthetic tissue cultures (47.1%) were considered positive, all revealing the same microbial species with the respective sonication fluid cultures: 3 tissue samples showed polymicrobial infection. All tissue cultures were also found positive by the sonication fluid culture.
CONCLUSIONS
Sonication fluid cultures represent a cheap, easy, accurate, and sensitive diagnostic modality demonstrating increased sensitivity compared to periprosthetic tissue cultures (70.5 versus 47.1%).
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery |
UniBE Contributor: |
Kohl, Sandro |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1537-744X |
Publisher: |
Hindawi Publishing Corporation |
Language: |
English |
Submitter: |
Stephanie Schmutz |
Date Deposited: |
21 May 2014 11:54 |
Last Modified: |
05 Dec 2022 14:29 |
Publisher DOI: |
10.1155/2013/375140 |
PubMed ID: |
24222731 |
BORIS DOI: |
10.7892/boris.42753 |
URI: |
https://boris.unibe.ch/id/eprint/42753 |
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