Rituximab as a treatment option for refractory endogenous anterior uveitis

Tappeiner, Christoph; Heinz, Carsten; Specker, Christof; Heiligenhaus, Arnd (2007). Rituximab as a treatment option for refractory endogenous anterior uveitis. Ophthalmic research, 39(3), pp. 184-186. Karger 10.1159/000103239

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BACKGROUND
To report on anti-CD20 antibody therapy in a patient with uveitis refractive to immunosuppression therapy.

METHODS
Case report with ophthalmoscopic, optical coherence tomography and fluorescein-angiographic findings.

RESULTS
A 49-year-old woman was suffering from bilateral, noninfectious chronic anterior uveitis refractive to corticosteroids and immunosuppressive drugs. Bilateral visual acuity was 20/100 due to cataract and cystoid macular edema (CME). After treatment with rituximab, vision and CME improved, and uveitis was stable until the final visit (follow-up at 12 months).

CONCLUSION
The case report suggests that rituximab may be helpful for selected patients with chronic anterior uveitis refractive to corticosteroids and immunosuppressive medication.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Tappeiner, Christoph

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0030-3747

Publisher:

Karger

Language:

English

Submitter:

Christoph Tappeiner

Date Deposited:

04 Mar 2014 10:06

Last Modified:

20 Dec 2014 04:03

Publisher DOI:

10.1159/000103239

PubMed ID:

17534119

BORIS DOI:

10.7892/boris.42894

URI:

https://boris.unibe.ch/id/eprint/42894

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