Non-invasive brain stimulation in neglect rehabilitation: an update

Müri, René Martin; Cazzoli, Dario; Nef, Tobias; Mosimann, Urs Peter; Hopfner, Simone; Nyffeler, Thomas (2013). Non-invasive brain stimulation in neglect rehabilitation: an update. Frontiers in human neuroscience, 7, p. 248. Frontiers Research Foundation 10.3389/fnhum.2013.00248

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Here, we review the effects of non-invasive brain stimulation such as transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS) in the rehabilitation of neglect. We found 12 studies including 172 patients (10 TMS studies and 2 tDCS studies) fulfilling our search criteria. Activity of daily living measures such as the Barthel Index or, more specifically for neglect, the Catherine Bergego Scale were the outcome measure in three studies. Five studies were randomized controlled trials with a follow-up time after intervention of up to 6 weeks. One TMS study fulfilled criteria for Class I and one for Class III evidence. The studies are heterogeneous concerning their methodology, outcome measures, and stimulation parameters making firm comparisons and conclusions difficult. Overall, there are however promising results for theta-burst stimulation, suggesting that TMS is a powerful add-on therapy in the rehabilitation of neglect patients.

Item Type:

Journal Article (Review Article)


10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Geriatric Psychiatry and Psychotherapy
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Pavillon 52 > Forschungsgruppe Perzeption und Okulomotorik

UniBE Contributor:

Müri, René Martin, Cazzoli, Dario, Nef, Tobias, Mosimann, Urs Peter, Hopfner, Simone, Nyffeler, Thomas


600 Technology > 610 Medicine & health




Frontiers Research Foundation




Pascal Wurtz

Date Deposited:

01 Apr 2014 11:34

Last Modified:

05 Dec 2022 14:29

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

rehabilitation review theta-burst protocol transcranial direct current stimulation transcranial magnetic stimulation unilateral neglect




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