True aneurysm of the peripheral pulmonary artery due to necrotizing giant cell arteritis

Steireif, Sven C.; Kocher, Gregor J.; Gebhart, Florin T. F.; Schmid, Ralph A. (2014). True aneurysm of the peripheral pulmonary artery due to necrotizing giant cell arteritis. European journal of cardio-thoracic surgery, 45(4), pp. 755-756. Oxford University Press 10.1093/ejcts/ezt411

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Pulmonary artery aneurysm in adults is a rare diagnosis. Most cases described in the literature are either associated with congenital heart disease or pulmonal arterial hypertension, respectively, or are not true aneurysms but rather pseudoaneurysms, which are usually iatrogenic. We present the case of a 68-year old female patient with the incidental finding of a true aneurysm of the right peripheral pulmonary artery with a maximum diameter of 4 cm. With increasing aneurysm diameter over time, the decision for a surgical resection was made. Complete resection of the aneurysm including lower lobe resection was performed. Histopathological examination showed necrotizing giant cell arteritis as the underlying cause. The postoperative course was uneventful and no signs of further disease activity were detected. To our knowledge, this is the first reported case of a pulmonary artery aneurysm caused by giant cell arteritis, whereas it should be noted that the distinction between Takayasu arteritis and giant cell arteritis is not clearly defined. Considering the high mortality associated with aneurysm rupture, surveillance is advocated for small aneurysms, whereas for larger aneurysms and those showing signs of progression in size despite medical therapy or even dissection, surgical intervention should be considered.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery
04 Faculty of Medicine > Service Sector > Institute of Pathology > Autopsy

UniBE Contributor:

Steireif, Sven Christoph; Kocher, Gregor; Gebhart, Florin and Schmid, Ralph

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1010-7940

Publisher:

Oxford University Press

Language:

English

Submitter:

Thomas Michael Marti

Date Deposited:

01 May 2014 14:21

Last Modified:

28 Oct 2019 20:10

Publisher DOI:

10.1093/ejcts/ezt411

PubMed ID:

23959741

Uncontrolled Keywords:

Giant cell arteritis, Pulmonary artery, Pulmonary artery aneurysm, Takayasu arteritis

BORIS DOI:

10.7892/boris.43250

URI:

https://boris.unibe.ch/id/eprint/43250

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