Quantification of Popliteal Artery Deformation During Leg Flexion in Subjects With Peripheral Artery Disease: A Pilot Study

Gökgöl, Can; Diehm, Nicolas Alexander; Kara, Levent; Büchler, Philippe (2013). Quantification of Popliteal Artery Deformation During Leg Flexion in Subjects With Peripheral Artery Disease: A Pilot Study. Journal of endovascular therapy, 20(6), pp. 828-835. International Society of Endovascular Specialists 10.1583/13-4332MR.1

[img] Text
Gökgöl-20-6-828.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (171kB) | Request a copy
[img]
Preview
Text
13-4332MR Gökgöl orig-PB.pdf - Accepted Version
Available under License Publisher holds Copyright.

Download (608kB) | Preview

Purpose: To quantify the in vivo deformations of the popliteal artery during leg flexion in subjects with clinically relevant peripheral artery disease (PAD). Methods: Five patients (4 men; mean age 69 years, range 56–79) with varying calcification levels of the popliteal artery undergoing endovascular revascularization underwent 3-dimensional (3D) rotational angiography. Image acquisition was performed with the leg straight and with a flexion of 70°/20° in the knee/hip joints. The arterial centerline and the corresponding branches in both positions were segmented to create 3D reconstructions of the arterial trees. Axial deformation, twisting, and curvatures were quantified. Furthermore, the relationships between the calcification levels and the deformations were investigated. Results: An average shortening of 5.9%±2.5% and twist rate of 3.8±2.2°/cm in the popliteal artery were observed. Maximal curvatures in the straight and flexed positions were 0.12±0.04 cm−1 and 0.24±0.09 cm−1, respectively. As the severity of calcification increased, the maximal curvature in the straight position increased from 0.08 to 0.17 cm−1, while an increase from 0.17 to 0.39 cm−1 was observed for the flexed position. Axial elongations and arterial twisting were not affected by the calcification levels. Conclusion: The popliteal artery of patients with symptomatic PAD is exposed to significant deformations during flexion of the knee joint. The severity of calcification directly affects curvature, but not arterial length or twisting angles. This pilot study also showed the ability of rotational angiography to quantify the 3D deformations of the popliteal artery in patients with various levels of calcification.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Gökgöl, Can; Diehm, Nicolas Alexander; Kara, Levent and Büchler, Philippe

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1526-6028

Publisher:

International Society of Endovascular Specialists

Language:

English

Submitter:

Philippe Büchler

Date Deposited:

12 May 2014 12:04

Last Modified:

08 Sep 2016 07:57

Publisher DOI:

10.1583/13-4332MR.1

PubMed ID:

24325701

Uncontrolled Keywords:

popliteal artery, femoropopliteal segment, 3D rotational angiography, computed tomography, knee flexion, peripheral artery disease, stenosis, 3D arterial reconstruction, arterial calcification, axial deformation, maximal curvature, twist rate

BORIS DOI:

10.7892/boris.43290

URI:

https://boris.unibe.ch/id/eprint/43290

Actions (login required)

Edit item Edit item
Provide Feedback