Bone conduction in Thiel-embalmed cadaver heads

Guignard, Jérémie; Stieger, Christof; Kompis, Martin; Caversaccio, Marco; Arnold, Andreas (2013). Bone conduction in Thiel-embalmed cadaver heads. Hearing research, 306, pp. 115-122. Elsevier 10.1016/j.heares.2013.10.002

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INTRODUCTION Sound can reach the inner ear via at least two different pathways: air conduction and bone conduction (BC). BC hearing is used clinically for diagnostic purposes and for BC hearing aids. Research on the motion of the human middle ear in response to BC stimulation is typically conducted using cadaver models. We evaluated middle ear motion of Thiel-embalmed whole-head specimens in terms of linearity, reproducibility, and consistency with the reported middle ear motion of living subjects, fresh cadaveric temporal bones, and whole-heads embalmed with a Non-Thiel solution of salts. METHODS We used laser Doppler vibrometry to measure the displacement of the skull, the umbo, the cochlear promontory, the stapes, and the round window in seven ears from four human whole-head specimens embalmed according to Thiel's method. The ears were stimulated with a Baha(®) implanted behind the auricle. RESULTS The Thiel model shows promontory velocity similar to that reported in the literature for whole-heads embalmed with a Non-Thiel solution of salts (0- to 7-dB difference). The Thiel heads' relative velocity of the stapes with respect to the promontory was similar to that of fresh cadaver temporal bones (0- to 4-dB difference). The velocity of the umbo was comparable in Thiel-embalmed heads and living subjects (0- to 10-dB difference). The skull and all middle ear elements measured responded linearly to different stimulation levels, with an average difference less than 1 dB. The variability of repeated measurements for both short- (2 h; 4 dB) and long-term (4-16 weeks; 6 dB) repetitions in the same ear, and the difference between the two ears of the same donor (approximately 10 dB) were lower than the inter-individual difference (up to 25 dB). CONCLUSION Thiel-embalmed human whole-head specimens can be used as an alternative model for the study of human middle ear mechanics secondary to BC stimulation. At some frequencies, differences from living subjects must be considered.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Pavillon 52 > Forschungsgruppe Audiologie
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Image Guided Therapy > ARTORG Center - Artificial Hearing Research

UniBE Contributor:

Guignard, Jérémie; Stieger, Christof; Kompis, Martin; Caversaccio, Marco and Arnold, Andreas Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0378-5955

Publisher:

Elsevier

Language:

English

Submitter:

Martin Kompis

Date Deposited:

05 Mar 2014 16:58

Last Modified:

20 May 2014 13:21

Publisher DOI:

10.1016/j.heares.2013.10.002

PubMed ID:

24161399

Uncontrolled Keywords:

air conduction, bone conduction, cochlear promontory, laser Doppler vibrometer, root-mean-square deviation, round window, skull, standard deviation, stapes, tympanic membrane

URI:

https://boris.unibe.ch/id/eprint/43535

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