Preventing erosion with novel agents

Wang, Xiaojie; Megert, Brigitte; Hellwig, Elmar; Neuhaus, Klaus; Lussi, Adrian (2011). Preventing erosion with novel agents. Journal of dentistry, 39(2), pp. 163-170. Oxford: Elsevier Science 10.1016/j.jdent.2010.11.007

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Objectives: This in vitro study aimed to investigate the protective effect of four commercial novel agents against erosion. Methods: Ninety human molars were distributed into 9 groups, and after incubation in human saliva for 2 h, a pellicle was formed. Subsequently, the specimens were submitted to demineralization (orange juice, pH 3.6, 3 min) and remineralization (paste slurry containing one of the tested novel agents, 3 min) cycles, two times per day, for 4 days. The tested agents were: (1) DenShield Tooth; active ingredient: 7.5% W/W NovaMin® (calcium sodium phosphosilicate); (2) Nanosensitive hca; active ingredient: 7.5% W/W NovaMin®; (3) GC Tooth Mousse; active ingredient: 10% Recaldent™ (CPP-ACP); (4) GC MI Paste Plus; active ingredients: 10% Recaldent™, 900 ppm fluoride. Two experimental procedures were performed: in procedure 1, the tested agents were applied prior to the erosive attack, and in procedure 2 after the erosive attack. A control group receiving no prophylactic treatment was included. Surface nanohardness (SNH) of enamel specimens was measured after pellicle formation and after completion of daily cyclic treatment. Results: SNH significantly decreased at the end of the experiment for all groups (p < 0.05). In both procedures, there was no statistically significant difference between the control group and those treated with paste slurries (p > 0.05). In addition, the changes in SNH (ΔSNH = SNHbaseline − SNHfinal) did not show statistically significant difference between both procedures (p > 0.05). Conclusion: Tooth erosion cannot be prevented or repaired by these novel agents, regardless of fluoride content.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry
04 Faculty of Medicine > School of Dental Medicine > Division of Fixed Prosthodontics (discontinued)

UniBE Contributor:

Wang, Xiaojie; Megert, Brigitte; Neuhaus, Klaus and Lussi, Adrian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0300-5712

Publisher:

Elsevier Science

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 14:16

Last Modified:

25 Jan 2017 12:16

Publisher DOI:

10.1016/j.jdent.2010.11.007

PubMed ID:

21126556

Web of Science ID:

000287060700010

BORIS DOI:

10.7892/boris.4394

URI:

https://boris.unibe.ch/id/eprint/4394 (FactScience: 208591)

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