Darsow, Ulf; Wollenberg, Andreas; Simon, Dagmar; Taïeb, Alain; Werfel, Thomas; Oranje, Arnold; Svensson, Ake; Deleuran, Mette; Gelmetti, Carlo; Calza, Anne-Marie; Giusti, Francesca; Lübbe, Jann; Seidenari, Stefania; Ring, Johannes; European Task Force on Atopic Dermatitis / EADV Eczema Task, the (2013). Difficult to control atopic dermatitis. World Allergy Organization journal, 6(1), p. 6. BioMed Central 10.1186/1939-4551-6-6
|
Text
1939-4551-6-6.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (783kB) | Preview |
Difficult to control atopic dermatitis (AD) presents a therapeutic challenge and often requires combinations of topical and systemic treatment. Anti-inflammatory treatment of severe AD most commonly includes topical glucocorticosteroids and topical calcineurin antagonists used for exacerbation management and more recently for proactive therapy in selected cases. Topical corticosteroids remain the mainstay of therapy, the topical calcineurin inhibitors tacrolimus and pimecrolimus are preferred in certain locations. Systemic anti-inflammatory treatment is an option for severe refractory cases. Microbial colonization and superinfection contribute to disease exacerbation and thus justify additional antimicrobial / antiseptic treatment. Systemic antihistamines (H1) may relieve pruritus but do not have sufficient effect on eczema. Adjuvant therapy includes UV irradiation preferably of UVA1 wavelength. "Eczema school" educational programs have been proven to be helpful.
Item Type: |
Journal Article (Review Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Simon, Dagmar |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1939-4551 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Monika Schenk |
Date Deposited: |
15 May 2014 11:22 |
Last Modified: |
05 Dec 2022 14:29 |
Publisher DOI: |
10.1186/1939-4551-6-6 |
PubMed ID: |
23663504 |
BORIS DOI: |
10.7892/boris.44073 |
URI: |
https://boris.unibe.ch/id/eprint/44073 |