Serial CT features of pulmonary leptospirosis in 10 dogs.

Gendron, Karine; Christe, Andreas; Walther, Sandro; Schweighauser, Ariane; Francey, Thierry; Doherr, Marcus; Lang, Johann (2014). Serial CT features of pulmonary leptospirosis in 10 dogs. Veterinary record, 174(7), p. 169. British Veterinary Association 10.1136/vr.102046

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Leptospirosis pulmonary haemorrhage syndrome (LPHS) is a frequent manifestation of Leptospira infection in dogs and is associated with a high morbidity and mortality. Three helical 16-slice thoracic CT scans were performed in 10 dogs naturally infected with Leptospira, within 24 hours of admission, and three and seven days later. Patients were sedated and scanned without breathhold, with a protocol adapted for rapid scanning. One dog died of respiratory failure on the morning following the first scan. On the initial scan, imaging features of LPHS included ground-glass nodules (10/10), peribronchovascular interstitial thickening (10/10), diffuse or patchy ground-glass opacity (9/10), solid nodules (8/10) and consolidation (7/10). Temporary bronchiolar dilation was observed in all dogs in association with peribronchovascular interstitial thickening, which had completely resolved at day 7. Nodules were with few exceptions assigned to the centrilobular region. Regression of lesion severity was observed after each subsequent scan. Consolidation and solid nodules changed over time into lesions of ground-glass attenuation. Pleural effusion (3/10) and mediastinal effusion (2/10) were mild and transient. Lesion severity appeared unassociated with survival to discharge.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Radiology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute

UniBE Contributor:

Gendron, Karine; Christe, Andreas; Walther, Sandro; Schweighauser, Ariane; Francey, Thierry; Doherr, Marcus and Lang, Johann

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0042-4900

Publisher:

British Veterinary Association

Language:

English

Submitter:

Susanne Portner

Date Deposited:

22 Aug 2014 15:48

Last Modified:

26 Jun 2016 01:48

Publisher DOI:

10.1136/vr.102046

PubMed ID:

24420873

BORIS DOI:

10.7892/boris.44232

URI:

https://boris.unibe.ch/id/eprint/44232

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