Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence - a multi-centre study

Otto, Sven; Abu-Id, Mario Hakim; Fedele, Stefano; Warnke, Patrick H; Becker, Stephan T; Kolk, Andreas; Mücke, Thomas; Mast, Gerson; Köhnke, Robert; Volkmer, Elias; Haasters, Florian; Lieger, Olivier; Iizuka, Tateyuki; Porter, Stephen; Campisi, Giuseppina; Colella, Giuseppe; Ploder, Oliver; Neff, Andreas; Wiltfang, Jörg; Ehrenfeld, Michael; ... (2011). Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence - a multi-centre study. Journal of cranio-maxillo-facial surgery, 39(4), pp. 272-277. Oxford: Elsevier 10.1016/j.jcms.2010.05.009

[img] Text
1-s2.0-S1010518210001307-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (389kB) | Request a copy

Bisphosphonates (BPs) are powerful drugs that inhibit bone metabolism. Adverse side effects are rare but potentially severe such as bisphosphonate-related osteonecrosis of the jaw (BRONJ). To date, research has primarily focused on the development and progression of BRONJ in cancer patients with bone metastasis, who have received high dosages of BPs intravenously. However, a potential dilemma may arise from a far larger cohort, namely the millions of osteoporosis patients on long-term oral BP therapy.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Lieger, Olivier and Iizuka, Tateyuki

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1010-5182

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:08

Last Modified:

07 Dec 2014 01:16

Publisher DOI:

10.1016/j.jcms.2010.05.009

PubMed ID:

20580566

Web of Science ID:

000291459000010

BORIS DOI:

10.7892/boris.443

URI:

https://boris.unibe.ch/id/eprint/443 (FactScience: 199295)

Actions (login required)

Edit item Edit item
Provide Feedback