Optimal sequence timing of CT angiography and perfusion CT in patients with stroke

Morhard, D; Wirth, Christina Doris; Reiser, M F; Schulte-Altedorneburg, G; Ertl-Wagner, B (2013). Optimal sequence timing of CT angiography and perfusion CT in patients with stroke. European journal of radiology, 82(6), e286-e289. Elsevier 10.1016/j.ejrad.2013.01.011

Full text not available from this repository.

OBJECTIVE

Standard stroke CT protocols start with non-enhanced CT followed by perfusion-CT (PCT) and end with CTA. We aimed to evaluate the influence of the sequence of PCT and CTA on quantitative perfusion parameters, venous contrast enhancement and examination time to save critical time in the therapeutic window in stroke patients.

METHODS AND MATERIALS

Stroke CT data sets of 85 patients, 47 patients with CTA before PCT (group A) and 38 with CTA after PCT (group B) were retrospectively analyzed by two experienced neuroradiologists. Parameter maps of cerebral blood flow, cerebral blood volume, time to peak and mean transit time and contrast enhancements (arterial and venous) were compared.

RESULTS

Both readers rated contrast of brain-supplying arteries to be equal in both groups (p=0.55 (intracranial) and p=0.73 (extracranial)) although the extent of venous superimposition of the ICA was rated higher in group B (p=0.04). Quantitative perfusion parameters did not significantly differ between the groups (all p>0.18), while the extent of venous superimposition of the ICA was rated higher in group B (p=0.04). The time to complete the diagnostic CT examination was significantly shorter for group A (p<0.01).

CONCLUSION

Performing CTA directly after NECT has no significant effect on PCT parameters and avoids venous preloading in CTA, while examination times were significantly shorter.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine
UniBE Contributor:	Wirth, Christina Doris
Subjects:	600 Technology > 610 Medicine & health
ISSN:	0720-048X
Publisher:	Elsevier
Language:	English
Submitter:	Patricia Rajaonina
Date Deposited:	01 Apr 2014 08:24
Last Modified:	05 Dec 2022 14:29
Publisher DOI:	10.1016/j.ejrad.2013.01.011
PubMed ID:	23394760
URI:	https://boris.unibe.ch/id/eprint/44406