Delayed diagnosis of cryptococcal meningoencephalitis due to negative cryptococcal antigen test

Kessler, B.; Bally, F.; Hewer, Ekkehard; Sendi, Parham (2013). Delayed diagnosis of cryptococcal meningoencephalitis due to negative cryptococcal antigen test. BMJ case reports, 2013(jan29 1), bcr2012007980-bcr2012007980. BMJ Publishing Group 10.1136/bcr-2012-007980

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Cryptococcus spp. commonly causes infection in immunocompromised hosts. Clinical presentation of cryptococcal meningoencephalitis (CM) is variable, but headache, fever and a high intracranial pressure should suggest the diagnosis. The cryptococcal antigen test is a specific and sensitive rapid test that can be performed on blood or cerebrospinal fluid. We report a case of CM in a patient with previously undetected lymphocytopenia. Because cryptococcal antigen test results were negative, diagnosis and treatment were delayed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Hewer, Ekkehard and Sendi, Parham

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1757-790X

Publisher:

BMJ Publishing Group

Language:

English

Submitter:

Annelies Luginbühl

Date Deposited:

21 Mar 2014 11:08

Last Modified:

28 Nov 2020 02:23

Publisher DOI:

10.1136/bcr-2012-007980

PubMed ID:

23365165

URI:

https://boris.unibe.ch/id/eprint/44592

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