Evaluation of the benefit of emergency vaccination in a foot-and-mouth disease free country with low livestock density

Dürr, Salome Esther; Fasel-Clemenz, Céline; Thür, Barbara; Schwermer, Heinzpeter; Doherr, Marcus G.; zu Dohna, Heinrich; Carpenter, Tim E.; Perler, Lukas; Hadorn, Daniela C. (2014). Evaluation of the benefit of emergency vaccination in a foot-and-mouth disease free country with low livestock density. Preventive veterinary medicine, 113(1), pp. 34-46. Elsevier 10.1016/j.prevetmed.2013.10.015

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Foot-and-mouth disease (FMD) is highly contagious and one of the most economically devastating diseases of cloven-hoofed animals. Scientific-based preparedness about how to best control the disease in a previously FMD-free country is therefore essential for veterinary services. The present study used a spatial, stochastic epidemic simulation model to compare the effectiveness of emergency vaccination with conventional (non-vaccination) control measures in Switzerland, a low-livestock density country. Model results revealed that emergency vaccination with a radius of 3 km or 10 km around infected premises (IP) did not significantly reduce either the cumulative herd incidence or epidemic duration if started in a small epidemic situation where the number of IPs is still low. However, in a situation where the epidemic has become extensive, both the cumulative herd incidence and epidemic duration are reduced significantly if vaccination were implemented with a radius of 10 km around IPs. The effect of different levels of conventional strategy measures was also explored for the non-vaccination strategy. It was found that a lower compliance level of farmers for movement restrictions and delayed culling of IPs significantly increased both the cumulative IP incidence and epidemic duration. Contingency management should therefore focus mainly on improving conventional strategies, by increasing disease awareness and communication with stakeholders and preparedness of culling teams in countries with a livestock structure similar to Switzerland; however, emergency vaccination should be considered if there are reasons to believe that the epidemic may become extensive, such as when disease detection has been delayed and many IPs are discovered at the beginning of the epidemic.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Dürr, Salome Esther; Thür, Barbara and Doherr, Marcus

Subjects:

600 Technology > 630 Agriculture

ISSN:

0167-5877

Publisher:

Elsevier

Language:

English

Submitter:

Susanne Portner

Date Deposited:

08 Aug 2014 07:41

Last Modified:

17 Aug 2018 11:45

Publisher DOI:

10.1016/j.prevetmed.2013.10.015

PubMed ID:

24211105

Uncontrolled Keywords:

Infectious disease, Livestock, Contingency management, Epidemiological model, Stochastic model, Control strategies, Switzerland

BORIS DOI:

10.7892/boris.44877

URI:

https://boris.unibe.ch/id/eprint/44877

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