Interferons in hematopoiesis and leukemia

Schürch, Christian M.; Riether, Carsten; Ochsenbein, Adrian F. (2013). Interferons in hematopoiesis and leukemia. Oncoimmunology, 2(6), e24572. Landes Bioscience 10.4161/onci.24572

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Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Schürch, Christian; Riether, Carsten and Ochsenbein, Adrian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2162-4011

Publisher:

Landes Bioscience

Language:

English

Submitter:

Marianne Zahn

Date Deposited:

12 May 2014 11:05

Last Modified:

05 Dec 2014 15:38

Publisher DOI:

10.4161/onci.24572

PubMed ID:

23894719

Uncontrolled Keywords:

hematopoiesis, hematopoietic stem cells, interferon, leukemia, leukemia stem cells

BORIS DOI:

10.7892/boris.45041

URI:

https://boris.unibe.ch/id/eprint/45041

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