Adaptive evolution during an ongoing range expansion: the invasive bank vole (Myodes glareolus) in Ireland

White, Thomas A.; Perkins, Sarah E.; Heckel, Gerald; Searle, Jeremy B. (2013). Adaptive evolution during an ongoing range expansion: the invasive bank vole (Myodes glareolus) in Ireland. Molecular Ecology, 22(11), pp. 2971-2985. Wiley-Blackwell 10.1111/mec.12343

[img] Text
white_heckel.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (358kB) | Request a copy

Range expansions are extremely common, but have only recently begun to attract attention in terms of their genetic consequences. As populations expand, demes at the wave front experience strong genetic drift, which is expected to reduce genetic diversity and potentially cause ‘allele surfing’, where alleles may become fixed over a wide geographical area even if their effects are deleterious. Previous simulation models show that range expansions can generate very strong selective gradients on dispersal, reproduction, competition and immunity. To investigate the effects of range expansion on genetic diversity and adaptation, we studied the population genomics of the bank vole (Myodes glareolus) in Ireland. The bank vole was likely introduced in the late 1920s and is expanding its range at a rate of ~2.5 km/year. Using genotyping-by-sequencing, we genotyped 281 bank voles at 5979 SNP loci. Fourteen sample sites were arranged in three transects running from the introduction site to the wave front of the expansion. We found significant declines in genetic diversity along all three transects. However, there was no evidence that sites at the wave front had accumulated more deleterious mutations. We looked for outlier loci with strong correlations between allele frequency and distance from the introduction site, where the direction of correlation was the same in all three transects. Amongst these outliers, we found significant enrichment for genic SNPs, suggesting the action of selection. Candidates for selection included several genes with immunological functions and several genes that could influence behaviour.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Population Genetics
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)

UniBE Contributor:

White, Thomas and Heckel, Gerald

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0962-1083

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Isabelle Duperret

Date Deposited:

04 Aug 2014 16:55

Last Modified:

08 Sep 2015 11:02

Publisher DOI:

10.1111/mec.12343

Additional Information:

Special Issue: Genotyping by Sequencing in Ecological and Conservation Genomics

Uncontrolled Keywords:

allele frequency cline, genotyping-by-sequencing, nonmodel, outlier, population genomics, RAD

BORIS DOI:

10.7892/boris.45502

URI:

https://boris.unibe.ch/id/eprint/45502

Actions (login required)

Edit item Edit item
Provide Feedback