Television viewing, C-reactive protein, and depressive symptoms in older adults

Hamer, Mark; Poole, Lydia; Messerli-Bürgy, Nadine (2013). Television viewing, C-reactive protein, and depressive symptoms in older adults. Brain, behavior, and immunity, 33, pp. 29-32. Elsevier 10.1016/j.bbi.2013.05.001

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There is emerging evidence for a link between sedentary behavior and mental health, although the mechanisms remain unknown. We tested if an underlying inflammatory process explains the association between sedentary behavior and depressive symptoms. We conducted a two year follow-up of 4964 (aged 64.5 ± 8.9 years) men and women from the English Longitudinal Study of Ageing, a cohort of community dwelling older adults. Self-reported TV viewing time was assessed at baseline as a marker of leisure time sedentary behavior. The eight-item Centre of Epidemiological Studies Depression (CES-D) scale was administered to measure depressive symptoms at follow-up. At baseline, TV time was associated with C-reactive protein (CRP), adjusted geometric mean CRP values were 2.94 mg/L (<2 h/d TV); 3.04 mg/L (2–4 h/d TV); 3.29 mg/L (4–6 h/d TV); 3.23 mg/L (>6 h/d TV). We observed both a direct association of TV time on CES-D score at follow-up (B = 0.08, 95% CI, 0.05, 0.10) and indirect effects (B = 0.07, 95% CI, 0.05, 0.08). The indirect effects were largely explained through lack of physical activity, smoking, and alcohol, but not by CRP or body mass index.

Item Type:

Journal Article (Original Article)


07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy
07 Faculty of Human Sciences > Institute of Psychology

UniBE Contributor:

Messerli, Nadine


100 Philosophy > 150 Psychology
600 Technology > 610 Medicine & health








Adriana Biaggi

Date Deposited:

24 Apr 2014 17:10

Last Modified:

20 Oct 2015 09:59

Publisher DOI:


Uncontrolled Keywords:

Sedentary, Depression, Ageing, Epidemiology, Inflammation, C-reactive protein




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