The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention

Klein, Jan Philipp; Berger, Thomas; Schröder, Johanna; Späth, Christina; Meyer, Björn; Caspar, Franz; Lutz, Wolfgang; Greiner, Wolfgang; Hautzinger, Martin; Rose, Matthias; Gräfe, Viola; Hohagen, Fritz; Andersson, Gerhard; Vettorazzi, Eik; Moritz, Steffen (2013). The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention. BMC psychiatry, 13(239), p. 239. BioMed Central 10.1186/1471-244X-13-239

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BACKGROUND:
Depressive disorders are among the leading causes of worldwide disability with mild to moderate forms of depression being particularly common. Low-intensity treatments such as online psychological treatments may be an effective way to treat mild to moderate depressive symptoms and prevent the emergence or relapse of major depression.

METHODS/DESIGN:
This study is a currently recruiting multicentre parallel-groups pragmatic randomized-controlled single-blind trial. A total of 1000 participants with mild to moderate symptoms of depression from various settings including in- and outpatient services will be randomized to an online psychological treatment or care as usual (CAU). We hypothesize that the intervention will be superior to CAU in reducing depressive symptoms assessed with the Personal Health Questionnaire (PHQ-9, primary outcome measure) following the intervention (12 wks) and at follow-up (24 and 48 wks). Further outcome parameters include quality of life, use of health care resources and attitude towards online psychological treatments.

DISCUSSION:
The study will yield meaningful answers to the question of whether online psychological treatment can contribute to the effective and efficient prevention and treatment of mild to moderate depression on a population level with a low barrier to entry.

TRIAL REGISTRATION:
Trial Registration Number: NCT01636752.

Item Type:

Journal Article (Original Article)

Division/Institute:

07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy

UniBE Contributor:

Berger, Thomas and Caspar, Franz

Subjects:

600 Technology > 610 Medicine & health
100 Philosophy > 150 Psychology

ISSN:

1471-244X

Publisher:

BioMed Central

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Thomas Berger

Date Deposited:

24 Apr 2014 17:05

Last Modified:

26 Jun 2016 01:49

Publisher DOI:

10.1186/1471-244X-13-239

PubMed ID:

24074299

BORIS DOI:

10.7892/boris.46106

URI:

https://boris.unibe.ch/id/eprint/46106

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