Geometry-Aware Multiscale Image Registration via OBBTree-Based Polyaffine Log-Demons

Seiler, Christof; Pennec, Xavier; Reyes, Mauricio (2011). Geometry-Aware Multiscale Image Registration via OBBTree-Based Polyaffine Log-Demons. In: Gabor, Fichtinger; Martel, Anne; Peters, Terry (eds.) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2011. 14th International Conference. Lecture Notes in Computer Science: Vol. 6892 (pp. 631-638). Berlin: Springer 10.1007/978-3-642-23629-7_77

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Non-linear image registration is an important tool in many areas of image analysis. For instance, in morphometric studies of a population of brains, free-form deformations between images are analyzed to describe the structural anatomical variability. Such a simple deformation model is justified by the absence of an easy expressible prior about the shape changes. Applying the same algorithms used in brain imaging to orthopedic images might not be optimal due to the difference in the underlying prior on the inter-subject deformations. In particular, using an un-informed deformation prior often leads to local minima far from the expected solution. To improve robustness and promote anatomically meaningful deformations, we propose a locally affine and geometry-aware registration algorithm that automatically adapts to the data. We build upon the log-domain demons algorithm and introduce a new type of OBBTree-based regularization in the registration with a natural multiscale structure. The regularization model is composed of a hierarchy of locally affine transformations via their logarithms. Experiments on mandibles show improved accuracy and robustness when used to initialize the demons, and even similar performance by direct comparison to the demons, with a significantly lower degree of freedom. This closes the gap between polyaffine and non-rigid registration and opens new ways to statistically analyze the registration results.

Item Type:

Conference or Workshop Item (Paper)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB [discontinued]

UniBE Contributor:

Seiler, Christof, Reyes Aguirre, Mauricio Antonio


500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health






Lecture Notes in Computer Science






Mauricio Antonio Reyes Aguirre

Date Deposited:

04 Oct 2013 14:16

Last Modified:

02 Mar 2023 23:20

Publisher DOI:


Web of Science ID:




URI: (FactScience: 209193)

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