Implementation of a virtual correlative light and transmission electron microscope

Voigt, Tilman; Zuber, Benoît; Gawatz, Gerlinde; Herrmann, Gudrun (2013). Implementation of a virtual correlative light and transmission electron microscope. Microscopy research and technique, 76(7), pp. 679-686. Wiley-Liss 10.1002/jemt.22218

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In the long run, the widespread use of slide scanners by pathologists requires an adaptation of teaching methods in histology and cytology in order to target these new possibilities of image processing and presentation via the internet. Accordingly, we were looking for a tool with the possibility to teach microscopic anatomy, histology, and cytology of tissue samples which would be able to combine image data from light and electron microscopes independently of microscope suppliers. With the example of a section through the villus of jejunum, we describe here how to process image data from light and electron microscopes in order to get one image-stack which allows a correlation of structures from the microscopic anatomic to the cytological level. With commercially available image-presentation software that we adapted to our needs, we present here a platform which allows for the presentation of this new but also of older material independently of microscope suppliers.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy

UniBE Contributor:

Voigt, Tilman; Zuber, Benoît and Herrmann, Gudrun


600 Technology > 610 Medicine & health








Benoît Zuber

Date Deposited:

20 Mar 2014 20:06

Last Modified:

20 Mar 2014 20:07

Publisher DOI:


PubMed ID:



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