A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: results of the Pleasant Events Program (PEP).

Moore, Raeanne C.; Chattillion, Elizabeth A.; Ceglowski, Jennifer; Ho, Jennifer; von Känel, Roland; Mills, Paul J.; Ziegler, Michael G.; Patterson, Thomas L.; Grant, Igor; Mausbach, Brent T. (2013). A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: results of the Pleasant Events Program (PEP). Behaviour research and therapy, 51(10), pp. 623-632. Elsevier 10.1016/j.brat.2013.07.005

[img] Text
Behav_Res_Ther_2013.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (475kB)

Dementia caregiving is associated with elevations in depressive symptoms and increased risk for cardiovascular diseases (CVD). This study evaluated the efficacy of the Pleasant Events Program (PEP), a 6-week Behavioral Activation intervention designed to reduce CVD risk and depressive symptoms in caregivers. One hundred dementia family caregivers were randomized to either the 6-week PEP intervention (N = 49) or a time-equivalent Information-Support (IS) control condition (N = 51). Assessments were completed pre- and post-intervention and at 1-year follow-up. Biological assessments included CVD risk markers Interleukin-6 (IL-6) and D-dimer. Psychosocial outcomes included depressive symptoms, positive affect, and negative affect. Participants receiving the PEP intervention had significantly greater reductions in IL-6 (p = .040), depressive symptoms (p = .039), and negative affect (p = .021) from pre- to post-treatment. For IL-6, clinically significant improvement was observed in 20.0% of PEP participants and 6.5% of IS participants. For depressive symptoms, clinically significant improvement was found for 32.7% of PEP vs 11.8% of IS participants. Group differences in change from baseline to 1-year follow-up were non-significant for all outcomes. The PEP program decreased depression and improved a measure of physiological health in older dementia caregivers. Future research should examine the efficacy of PEP for improving other CVD biomarkers and seek to sustain the intervention's effects.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology > Centre of Competence for Psychosomatic Medicine

UniBE Contributor:

von Känel, Roland

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0005-7967

Publisher:

Elsevier

Language:

English

Submitter:

Annette Barbara Kocher

Date Deposited:

13 Jun 2014 12:11

Last Modified:

05 Dec 2022 14:31

Publisher DOI:

10.1016/j.brat.2013.07.005

PubMed ID:

23916631

Uncontrolled Keywords:

Alzheimer's disease, Cardiovascular disease, Depression, Intervention, Treatment

BORIS DOI:

10.7892/boris.47256

URI:

https://boris.unibe.ch/id/eprint/47256

Actions (login required)

Edit item Edit item
Provide Feedback