Salvage Radiotherapy After Radical Prostatectomy

Papachristofilou, Alexandros; Ghadjar, Pirus; Zimmermann, Frank (2013). Salvage Radiotherapy After Radical Prostatectomy. In: Medical Radiology (pp. 243-252). Berlin, Heidelberg: Springer 10.1007/174_2013_939

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Salvage radiation therapy is the sole curative treatment for patients experiencing biochemical relapse after radical surgical treatment of prostate cancer. The main dilemma in salvage radiation therapy is, whether or not biochemical relapse represents purely localized recurrent disease in the prostatic fossa or systemic micrometastasis. Initiating salvage radiation therapy at an early time point raises its chances of success, but may lead to overtreatment of patients. Target volume definition and treatment techniques are a matter of current research, with still many questions unanswered. Strategies of treatment escalation either by increasing the treatment dose or combining radiation therapy with androgen deprivation therapy are being addressed in clinical trials.

Item Type:

Book Section (Book Chapter)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Ghadjar, Pirus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0942-5373

Publisher:

Springer

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

24 Apr 2014 09:14

Last Modified:

26 Jun 2016 01:50

Publisher DOI:

10.1007/174_2013_939

URI:

https://boris.unibe.ch/id/eprint/47814

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