New Technologies and Concepts for Rehabilitation in the Acute Phase of Stroke: A Collaborative Matrix

Siekierka, E. M.; Eng, K.; Bassetti, Claudio; Blickenstorfer, A.; Cameirao, M. S.; Dietz, V.; Duff, A.; Erol, F.; Ettlin, T.; Hermann, D. M.; Keller, T.; Keisker, B.; Kesselring, J.; Kleiser, R.; Kollias, S.; Kool, J .P.; Kurre, A.; Mangold, S.; Nef, Tobias; Pyk, P.; ... (2007). New Technologies and Concepts for Rehabilitation in the Acute Phase of Stroke: A Collaborative Matrix. Neurodegenerative diseases, 4(1), pp. 57-69. Karger 10.1159/000100360

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The process of developing a successful stroke rehabilitation methodology requires four key components: a good understanding of the pathophysiological mechanisms underlying this brain disease, clear neuroscientific hypotheses to guide therapy, adequate clinical assessments of its efficacy on multiple timescales, and a systematic approach to the application of modern technologies to assist in the everyday work of therapists. Achieving this goal requires collaboration between neuroscientists, technologists and clinicians to develop well-founded systems and clinical protocols that are able to provide quantitatively validated improvements in patient rehabilitation outcomes. In this article we present three new applications of complementary technologies developed in an interdisciplinary matrix for acute-phase upper limb stroke rehabilitation – functional electrical stimulation, arm robot-assisted therapy and virtual reality-based cognitive therapy. We also outline the neuroscientific basis of our approach, present our detailed clinical assessment protocol and provide preliminary results from patient testing of each of the three systems showing their viability for patient use.

Item Type:

Journal Article (Original Article)


10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Bassetti, Claudio L.A., Nef, Tobias


600 Technology > 610 Medicine & health
600 Technology > 620 Engineering








Vanessa Vallejo

Date Deposited:

04 Jul 2014 09:09

Last Modified:

02 Mar 2023 23:24

Publisher DOI:


Uncontrolled Keywords:

Stroke, Rehabilitation, Functional electrical stimulation, Arm robot-assisted therapy, Virtual reality, Mirror neuron


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