Stavropoulos, Andreas; Windisch, Péter; Szendröi-Kiss, Dora; Peter, Rosta; Gera, István; Sculean, Anton (2010). Clinical and histologic evaluation of granular Beta-tricalcium phosphate for the treatment of human intrabony periodontal defects: a report on five cases. Journal of periodontology, 81(2), pp. 325-34. Chicago, Ill.: American Academy of Periodontology 10.1902/jop.2009.090386
Full text not available from this repository.BACKGROUND: The aim of the study is to clinically and histologically evaluate the healing of advanced intrabony defects treated with open flap debridement and the adjunct implantation of granular beta tricalcium phosphate (beta-TCP). METHODS: Five patients, each displaying advanced combined 1- and 2-wall intrabony defects around teeth scheduled for extraction or root resection, were recruited. Approximately 6 months after surgery, the teeth or roots were removed together with a portion of their surrounding soft and hard tissues and processed for histologic evaluation. RESULTS: The mean probing depth (PD) was reduced from 10.8 +/- 2.3 mm presurgically to 4.6 +/- 2.1 mm, whereas a mean clinical attachment level (CAL) gain of 5.0 +/- 0.7 mm was observed. The increase in gingival recession was 1.2 +/- 3.2 mm. The histologic evaluation indicated the formation of new cellular cementum with inserting collagen fibers to a varying extent (mean: 1.9 +/- 0.7 mm; range: 1.2 to 3.03 mm) coronal to the most apical extent of the root instrumentation. The mean new bone formation was 1.0 +/- 0.7 mm (range: 0.0 to 1.9 mm). In most specimens, beta-TCP particles were embedded in the connective tissue, whereas the formation of a mineralized bone-like or cementum-like tissue around the particles was only occasionally observed. CONCLUSION: The present data indicates that treatment of intrabony periodontal defects with this beta-TCP may result in substantial clinical improvements such as PD reduction and CAL gain, but this beta-TCP does not seem to enhance the regeneration of cementum, periodontal ligament, and bone.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology |
UniBE Contributor: |
Sculean, Anton |
ISSN: |
0022-3492 |
Publisher: |
American Academy of Periodontology |
Language: |
English |
Submitter: |
Eveline Carmen Schuler |
Date Deposited: |
04 Oct 2013 14:08 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1902/jop.2009.090386 |
PubMed ID: |
20151813 |
Web of Science ID: |
000283020300020 |
URI: |
https://boris.unibe.ch/id/eprint/480 (FactScience: 199486) |
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