A robust reference signal generator for synchronized ventricular assist devices

Amacher, Raffael; Ochsner, Gregor; Ferreira, Antonio; Vandenberghe, Stijn; Daners, Marianne Schmid (2013). A robust reference signal generator for synchronized ventricular assist devices. IEEE transactions on biomedical engineering, 60(8), pp. 2174-2183. Institute of Electrical and Electronics Engineers IEEE 10.1109/TBME.2013.2251634

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Ventricular assist devices (VADs) are blood pumps that offer an option to support the circulation of patients with severe heart failure. Since a failing heart has a remaining pump function, its interaction with the VAD influences the hemodynamics. Ideally, the heart's action is taken into account for actuating the device such that the device is synchronized to the natural cardiac cycle. To realize this in practice, a reliable real-time algorithm for the automatic synchronization of the VAD to the heart rate is required. This paper defines the tasks such an algorithm needs to fulfill: the automatic detection of irregular heart beats and the feedback control of the phase shift between the systolic phases of the heart and the assist device. We demonstrate a possible solution to these problems and analyze its performance in two steps. First, the algorithm is tested using the MIT-BIH arrhythmia database. Second, the algorithm is implemented in a controller for a pulsatile and a continuous-flow VAD. These devices are connected to a hybrid mock circulation where three test scenarios are evaluated. The proposed algorithm ensures a reliable synchronization of the VAD to the heart cycle, while being insensitive to irregularities in the heart rate.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE) > ARTORG Center - Cardiovascular Engineering (Heart)

UniBE Contributor:

Vandenberghe, Stijn

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0018-9294

Publisher:

Institute of Electrical and Electronics Engineers IEEE

Language:

English

Submitter:

Francesco Clavica

Date Deposited:

16 Jun 2014 14:37

Last Modified:

02 Nov 2015 09:52

Publisher DOI:

10.1109/TBME.2013.2251634

URI:

https://boris.unibe.ch/id/eprint/48117

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