Electrocardiographic ST-segment monitoring during controlled occlusion of coronary arteries

Haeberlin, Andreas; Studer, Evelyn; Niederhauser, Thomas; Stoller, Michael; Marisa, Thanks; Götte, Josef; Jacomet, Marcel; Traupe, Tobias; Seiler, Christian; Vogel, Rolf (2014). Electrocardiographic ST-segment monitoring during controlled occlusion of coronary arteries. Journal of electrocardiology, 47(1), pp. 29-37. Elsevier 10.1016/j.jelectrocard.2013.10.003

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Background: Ischemia monitoring cannot always be performed by 12-lead ECG. Hence, the individual performance of the ECG leads is crucial. No experimental data on the ECG's specificity for transient ischemia exist. Methods: In 45 patients a 19-lead ECG was registered during a 1-minute balloon occlusion of a coronary artery (left anterior descending artery [LAD], right coronary artery [RCA] or left circumflex artery [LCX]). ST-segment shifts and sensitivity/specificity of the leads were measured. Results: During LAD occlusion, V3 showed maximal ST-segment elevation (0.26 mV [IQR 0.16–0.33 mV], p = 0.001) and sensitivity/specificity (88% and 80%). During RCA occlusion, III showed maximal ST-elevation (0.2 mV [IQR 0.09–0.26 mV], p = 0.004), aVF had the best sensitivity/specificity (85% and 68%). During LCX occlusion, V6 showed maximal ST-segment elevation (0.04 mV [IQR 0.02–0.14 mV], p = 0.005), and sensitivity/specificity was (31%/92%) but could be improved (63%/72%) using an optimized cut-off for ischemia. Conclusion: V3, aVF and V6 show the best performance to detect transient ischemia.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE) > ARTORG Center - Cardiovascular Engineering (Blood Vessel)
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE)

UniBE Contributor:

Häberlin, Andreas; Niederhauser, Thomas; Marisa, Thanks; Götte, Josef; Seiler, Christian and Vogel, Rolf

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1532-8430

Publisher:

Elsevier

Language:

English

Submitter:

Francesco Clavica

Date Deposited:

09 Apr 2014 16:00

Last Modified:

24 Apr 2017 17:39

Publisher DOI:

10.1016/j.jelectrocard.2013.10.003

BORIS DOI:

10.7892/boris.48135

URI:

https://boris.unibe.ch/id/eprint/48135

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