The origin of the 'Mycoplasma mycoides cluster' coincides with domestication of ruminants.

Fischer, Anne; Shapiro, Beth; Muriuki, Cecilia; Heller, Martin; Schnee, Christiane; Bongcam-Rudloff, Erik; Vilei, Edy M; Frey, Joachim; Jores, Joerg (2012). The origin of the 'Mycoplasma mycoides cluster' coincides with domestication of ruminants. PLoS ONE, 7(4), e36150. Public Library of Science 10.1371/journal.pone.0036150

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The 'Mycoplasma mycoides cluster' comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp. capricolum, Mycoplasma leachii and Mycoplasma mycoides subsp. capri. CBPP and CCPP are major livestock diseases and impact the agricultural sector especially in developing countries through reduced food-supply and international trade restrictions. In addition, these diseases are a threat to disease-free countries. We used a multilocus sequence typing (MLST) approach to gain insights into the demographic history of and phylogenetic relationships among the members of the 'M. mycoides cluster'. We collected partial sequences from seven housekeeping genes representing a total of 3,816 base pairs from 118 strains within this cluster, and five strains isolated from wild Caprinae. Strikingly, the origin of the 'M. mycoides cluster' dates to about 10,000 years ago, suggesting that the establishment and spread of the cluster coincided with livestock domestication. In addition, we show that hybridization and recombination may be important factors in the evolutionary history of the cluster.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Vilei, Edy and Frey, Joachim

Subjects:

600 Technology > 630 Agriculture

ISSN:

1932-6203

Publisher:

Public Library of Science

Language:

English

Submitter:

Andrea Stettler

Date Deposited:

28 Mar 2014 16:09

Last Modified:

07 Apr 2015 10:41

Publisher DOI:

10.1371/journal.pone.0036150

PubMed ID:

22558362

BORIS DOI:

10.7892/boris.48920

URI:

https://boris.unibe.ch/id/eprint/48920

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