Malignant solitary fibrous tumor involving the liver

Jakob, Manuel; Schneider, Matthias; Hoeller, Ingo; Laffer, Urban; Kaderli, Reto Martin (2013). Malignant solitary fibrous tumor involving the liver. World journal of gastroenterology, 19(21), p. 3354. WJG Press 10.3748/wjg.v19.i21.3354

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Solitary fibrous tumors are predominantly benign and are most commonly found in the thoracic cavity and pleura; while reports exist in the literature of malignant solitary fibrous tumors and those located in extrathoracic organs, these cases are considered extremely rare. Herein, a case is reported of a malignant solitary fibrous tumor involving the liver that was diagnosed and treated in a 62-year-old woman. The patient presented with complaints of upper abdominal pain and unintentional weight loss. Computed tomography scan of the abdomen revealed a remarkably large mass, measuring 15 cm × 10 cm × 20 cm, which appeared to be unrelated to any particular organ. The intraoperative finding of a wide communication with the left liver suggested hepatic origin, and served as an indicator for tumor resection via left hemihepatectomy. The diagnosis of solitary fibrous tumor and its malignant nature was confirmed by histological and immunohistochemical examination of the resected tissues. Hepatic solitary fibrous tumor is very rare, and surgery remains the mainstay of treatment. Due to limited reports of such tumors in the literature, little can be said about the benefit of adjuvant therapy and prognosis for the rare cases with malignant histological findings.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery

UniBE Contributor:

Schneider, Matthias; Laffer, Urban and Kaderli, Reto Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1007-9327

Publisher:

WJG Press

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

13 Jun 2014 11:11

Last Modified:

13 Dec 2014 08:11

Publisher DOI:

10.3748/wjg.v19.i21.3354

Uncontrolled Keywords:

Extrathoracic, Liver, Malignant, Mesenchymal neoplasm, Solitary fibrous tumor, Surgical resection

BORIS DOI:

10.7892/boris.49271

URI:

https://boris.unibe.ch/id/eprint/49271

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