Cerebral hemodynamic and oxygenation changes induced by inner and heard speech: a study combining functional near-infrared spectroscopy and capnography

Scholkmann, Felix; Klein, Sabine; Gerber, Ursina; Wolf, Martin; Wolf, Ursula (2014). Cerebral hemodynamic and oxygenation changes induced by inner and heard speech: a study combining functional near-infrared spectroscopy and capnography. Journal of biomedical optics, 19(1), 017002. SPIE International Society for Optical Engineering 10.1117/1.JBO.19.1.017002

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The aim of this study was to investigate the effects of inner and heard speech on cerebral hemodynamics and oxygenation in the anterior prefrontal cortex (PFC) using functional near-infrared spectroscopy and to test whether potential effects were caused by alterations in the arterial carbon dioxide pressure (PaCO2). Twenty-nine healthy adult volunteers performed six different tasks of inner and heard speech according to a randomized crossover design. During the tasks, we generally found a decrease in PaCO2 (only for inner speech), tissue oxygen saturation (StO2), oxyhemoglobin ([O2Hb]), total hemoglobin ([tHb]) concentration and an increase in deoxyhemoglobin concentration ([HHb]). Furthermore, we found significant relations between changes in [O2Hb], [HHb], [tHb], or StO2 and the participants’ age, the baseline PETCO2, or certain speech tasks. We conclude that changes in breathing during the tasks led to lower PaCO2 (hypocapnia) for inner speech. During heard speech, no significant changes in PaCO2 occurred, but the decreases in StO2, [O2Hb], and [tHb] suggest that changes in PaCO2 were also involved here. Different verse types (hexameter and alliteration) led to different changes in [tHb], implying different brain activations. In conclusion, StO2, [O2Hb], [HHb], and [tHb] are affected by interplay of both PaCO2 reactivity and functional brain activity.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM)

UniBE Contributor:

Scholkmann, Felix; Klein, Sabine and Wolf, Ursula

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1083-3668

Publisher:

SPIE International Society for Optical Engineering

Language:

English

Submitter:

Sabine Klein

Date Deposited:

09 Oct 2014 09:08

Last Modified:

26 Jun 2016 01:51

Publisher DOI:

10.1117/1.JBO.19.1.017002

BORIS DOI:

10.7892/boris.50497

URI:

https://boris.unibe.ch/id/eprint/50497

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