Baumann, Frederic; Diehm, Nicolas (2013). Restenosis after infrapopliteal angioplasty - clinical importance, study update and further directions. Vasa - European journal of vascular medicine, 42(6), pp. 413-420. Huber 10.1024/0301-1526/a000310
Full text not available from this repository.Patients with critical limb ischemia (CLI) represent the most severe form of peripheral arterial disease (PAD) and exhibit high mortality rates. Frequently, PAD in CLI patients involves the infrapopliteal arterial segment challenging endovascular revascularization strategies. Restenosis remains the major drawback of tibial angioplasty encountered in more than two thirds of CLI patients undergoing tibial revascularization. In contrast to earlier observations, tibial patency was recently shown to be essential to attain an optimal clinical outcome in CLI patients subsequent to tibial angioplasty. The exact pathopyhsiological mechanisms of tibial restenosis remains unclear. To date, most of our knowledge on tibial restenosis and its pathophysiology is derived from coronary arteries, based on the similarity of coronary arteries to tibial artery morphology. Nervertheless, multiple antirestenosis concepts are investigated within clinical trials to reduce tibial restenosis.Purpose of the present manuscript is to provide a current update on the pathophysiology of tibial restenosis and potential antirestenosis strategies.
Item Type: |
Journal Article (Review Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology |
UniBE Contributor: |
Diehm, Nicolas Alexander |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0301-1526 |
Publisher: |
Huber |
Language: |
English |
Submitter: |
Catherine Gut |
Date Deposited: |
09 Jul 2014 15:31 |
Last Modified: |
05 Dec 2022 14:33 |
Publisher DOI: |
10.1024/0301-1526/a000310 |
PubMed ID: |
24220117 |
Uncontrolled Keywords: |
Tibial angioplasty, antirestenosis, restenosis |
URI: |
https://boris.unibe.ch/id/eprint/50748 |