Engelberger, Rolf Peter; Kucher, Nils (2014). Ultrasound-assisted thrombolysis for acute pulmonary embolism: a systematic review. European Heart Journal, 35(12), pp. 758-764. Oxford University Press 10.1093/eurheartj/ehu029
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Pulmonary embolism remains a common and potentially life-threatening disease. For patients with intermediate- and high-risk pulmonary embolism, catheter-based revascularization therapy has emerged as potential alternative to systemic thrombolysis or surgical embolectomy. Ultrasound-assisted catheter-directed thrombolysis is a contemporary catheter-based technique and is the focus of the present review. Ultrasound-assisted catheter-directed thrombolysis is more effective in reversing right ventricular dysfunction and dilatation in comparison with anticoagulation alone in patients at intermediate risk. However, a direct comparison of ultrasound-assisted thrombolysis with systemic thrombolysis or surgical thrombectomy is not available. Ultrasound-assisted thrombolysis with initial intrapulmonary thrombolytic bolus may also be effective in high-risk patients, but evidence from randomized trials is not available. This review summarizes current data on ultrasound-assisted thrombolysis for acute pulmonary embolism.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology |
UniBE Contributor: |
Engelberger, Rolf Peter, Kucher, Nils |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0195-668X |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Catherine Gut |
Date Deposited: |
09 Oct 2014 09:51 |
Last Modified: |
05 Dec 2022 14:33 |
Publisher DOI: |
10.1093/eurheartj/ehu029 |
PubMed ID: |
24497337 |
Uncontrolled Keywords: |
Bleeding, Catheter-based revascularization, Pulmonary embolism, Ultrasound-assisted thrombolysis |
BORIS DOI: |
10.7892/boris.50760 |
URI: |
https://boris.unibe.ch/id/eprint/50760 |
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