Intentional and unintentional non-adherence to medications following an acute coronary syndrome: A longitudinal study

Molloy, Gerard J.; Messerli, Nadine; Hutton, Gemma; Wikman, Anna; Perkins-Porras, Linda; Steptoe, Andrew (2014). Intentional and unintentional non-adherence to medications following an acute coronary syndrome: A longitudinal study. Journal of psychosomatic research, 76(5), pp. 430-432. Elsevier 10.1016/j.jpsychores.2014.02.007

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Objective
Non-adherence to medication is common among coronary heart disease patients. Non-adherence to medication may be either intentional or unintentional. In this analysis we provide estimates of intentional and unintentional non-adherence in the year following an acute coronary syndrome (ACS).

Method
In this descriptive prospective observational study of patients with confirmed ACS medication adherence measures were derived from responses to the Medication Adherence Report Scale at approximately 2 weeks (n = 223), 6 months (n = 139) and 12 months (n = 136) following discharge from acute treatment for ACS.

Results
Total medication non-adherence was 20%, 54% and 53% at each of these time points respectively. The corresponding figures for intentional non-adherence were 8%, 15% and 15% and 15%, 52% and 53% for unintentional non-adherence. There were significant increases in the levels of medication non-adherence between the immediate discharge period (2 weeks) and 6 months that appeared to stabilize between 6 and 12 months after acute treatment for ACS.

Conclusion
Unintentional non-adherence to medications may be the primary form of non-adherence in the year following ACS. Interventions delivered early in the post-discharge period may prevent the relatively high levels of non-adherence that appear to become established by 6 months following an ACS.

Item Type:	Journal Article (Original Article)
Division/Institute:	07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy 07 Faculty of Human Sciences > Institute of Psychology
UniBE Contributor:	Messerli, Nadine
Subjects:	100 Philosophy > 150 Psychology 600 Technology > 610 Medicine & health
ISSN:	0022-3999
Publisher:	Elsevier
Language:	English
Submitter:	Adriana Biaggi
Date Deposited:	03 Jul 2014 14:55
Last Modified:	05 Dec 2022 14:33
Publisher DOI:	10.1016/j.jpsychores.2014.02.007
PubMed ID:	24745787
Uncontrolled Keywords:	Acute coronary syndrome, Adherence, Intention, Psychological
URI:	https://boris.unibe.ch/id/eprint/50769