Intussusceptive microvascular growth in tumors

Ribatti, Domenico; Djonov, Valentin (2012). Intussusceptive microvascular growth in tumors. Cancer letters, 316(2), pp. 126-31. Amsterdam: Elsevier 10.1016/j.canlet.2011.10.040

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Intussusception is an alternative to the sprouting mode of angiogenesis. The advantage of this mechanism of vascular growth is that blood vessels are generated more rapidly and the capillaries thereby formed are less leaky. This review article summarizes our current knowledge concerning the role played by intussusceptive microvascular growth in tumor growth. Interestingly, an angiogenic switch from sprouting to intussusceptive angiogenesis occurs after treatment with angiogenesis inhibitors and may be considered as a tumor-protective adaptative response.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy

UniBE Contributor:

Djonov, Valentin

ISSN:

0304-3835

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:17

Last Modified:

06 Dec 2013 13:25

Publisher DOI:

10.1016/j.canlet.2011.10.040

PubMed ID:

22197620

Web of Science ID:

000300811000002

URI:

https://boris.unibe.ch/id/eprint/5125 (FactScience: 209843)

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