Acid and Alkaline Etching of Sandblasted Zirconia Implants: A Histomorphometric Study in Miniature Pigs.

Saulacic, Nikola; Erdösi, Robert; Bosshardt, Dieter; Gruber, Reinhard; Buser, Daniel (2014). Acid and Alkaline Etching of Sandblasted Zirconia Implants: A Histomorphometric Study in Miniature Pigs. Clinical implant dentistry and related research, 16(3), pp. 313-322. Blackwell 10.1111/cid.12070

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BACKGROUND: Zirconia (ZrO2 ) has received interest as a dental material; however, little information is available on the impact of surface modifications on the osseointegration of zirconia implants. PURPOSE: The aim of the present study was to determine the effect of acid or alkaline etching of sandblasted ZrO2 implants on bone apposition in vivo. METHODS: Cylindrical ZrO2 implants with two circumferential grooves were placed in the maxilla of 12 miniature pigs. Biopsies were harvested after 1, 2, 4, and 8 weeks of healing. Undecalcified toluidine blue-stained ground sections were produced. The bone-to-implant contact, the bone area, and the presence of multinucleated giant cells were determined by histomorphometry. An uncorrected explorative statistical analysis was performed. RESULTS: Acid etching but not alkaline etching of sandblasted ZrO2 implants caused more bone-to-implant contact than sandblasted ZrO2 implants. The bone area was unaffected by the surface modifications. Acid and alkaline etching both increased the formation of multinucleated giant cells at the implant surface. CONCLUSIONS: This study provides a scientific basis to further investigate the impact of acid etching of sandblasted ZrO2 implants on osseointegration and the role of multinucleated giant cells in this process.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology
04 Faculty of Medicine > School of Dental Medicine > School of Dental Medicine, Oral Surgery Research
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Saulacic, Nikola; Bosshardt, Dieter; Gruber, Reinhard and Buser, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1523-0899

Publisher:

Blackwell

Language:

English

Submitter:

Caroline Dominique Zürcher

Date Deposited:

03 Jul 2014 15:09

Last Modified:

05 Nov 2015 11:48

Publisher DOI:

10.1111/cid.12070

PubMed ID:

23574426

BORIS DOI:

10.7892/boris.51439

URI:

https://boris.unibe.ch/id/eprint/51439

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