New MLSB resistance gene erm(43) in Staphylococcus lentus

Schwendener, Sybille; Perreten, Vincent (2012). New MLSB resistance gene erm(43) in Staphylococcus lentus. Antimicrobial agents and chemotherapy, 56(9), pp. 4746-4752. American Society for Microbiology 10.1128/AAC.00627-12

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The search for a specific rRNA methylase motif led to the identification of the new macrolide, lincosamide, and streptogramin B resistance gene erm(43) in Staphylococcus lentus. An inducible resistance phenotype was demonstrated by cloning and expressing erm(43) and its regulatory region in Staphylococcus aureus. The erm(43) gene was detected in two different DNA fragments, of 6,230 bp and 1,559 bp, that were each integrated at the same location in the chromosome in several S. lentus isolates of human, dog, and chicken origin.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology > Molecular Bacterial Epidemiology and Infectiology
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Schwendener, Sybille and Perreten, Vincent

Subjects:

600 Technology > 630 Agriculture

ISSN:

0066-4804

Publisher:

American Society for Microbiology

Language:

English

Submitter:

Vincent Perreten

Date Deposited:

30 Apr 2014 16:27

Last Modified:

08 Feb 2017 14:45

Publisher DOI:

10.1128/AAC.00627-12

PubMed ID:

22733067

URI:

https://boris.unibe.ch/id/eprint/52013

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