Hemodynamics and Flow Characteristics of a New Dialysis Port

Guignard, Jérémie; Terefe, Muluken Berhanu; Uehlinger, Dominik; Czerwinska, Justyna (2014). Hemodynamics and Flow Characteristics of a New Dialysis Port. ASAIO journal, 60(1), pp. 81-89. Lippincott Williams & Wilkins 10.1097/MAT.0000000000000015

Preview

Text 00002480-201401000-00015.pdf - Published Version Available under License Publisher holds Copyright. Download (4MB) | Preview

Renal replacement therapy by hemodialysis requires a permanent vascular access. Implantable ports offer a potential alternative to standard vascular access strategies although their development is limited both in number and extent. We explored the fluid dynamics within two new percutaneous bone-anchored dialysis port prototypes, both by in vitro experiments and computer simulation. The new port is to be fixed to bone and allows the connection of a dialysis machine to a central venous catheter via a built-in valve. We found that the pressure drop induced by the two ports was between 20 and 50 mmHg at 500 ml/min, which is comparable with commercial catheter connectors (15–80 mmHg). We observed the formation of vortices in both geometries, and a shear rate in the physiological range (<10,000s-1), which is lower than maximal shear rates reported in commercial catheters (up to 13,000s-1). A difference in surface shear rate of 15% between the two ports was obtained.

Interest & Impact

Downloads

457 since deposited on 12 Sep 2014
35 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item