Estimation of aortic pressure waveforms from 4D phase-contrast MRI

Delles, Michael; Rengier, Fabian; Jeong, Yoo-Jin; von Tengg-Kobligk, Hendrik; Ley, Sebastian; Kauczor, Hans-Ulrich; Dillmann, Rudiger; Unterhinninghofen, Roland (2013). Estimation of aortic pressure waveforms from 4D phase-contrast MRI. IEEE Engineering in Medicine and Biology Society conference proceedings, 2013, pp. 731-734. IEEE Service Center 10.1109/EMBC.2013.6609604

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Several approaches for the non-invasive MRI-based measurement of the aortic pressure waveform over the heart cycle have been proposed in the last years. These methods are normally based on time-resolved, two-dimensional phase-contrast sequences with uni-directionally encoded velocities (2D PC-MRI). In contrast, three-dimensional acquisitions with tridirectional velocity encoding (4D PC-MRI) have been shown to be a suitable data source for detailed investigations of blood flow and spatial blood pressure maps. In order to avoid additional MR acquisitions, it would be advantageous if the aortic pressure waveform could also be computed from this particular form of MRI. Therefore, we propose an approach for the computation of the aortic pressure waveform which can be completely performed using 4D PC-MRI. After the application of a segmentation algorithm, the approach automatically computes the aortic pressure waveform without any manual steps. We show that our method agrees well with catheter measurements in an experimental phantom setup and produces physiologically realistic results in three healthy volunteers.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

von Tengg-Kobligk, Hendrik


600 Technology > 610 Medicine & health




IEEE Service Center




Aisha Stefania Mzinga

Date Deposited:

13 May 2014 08:55

Last Modified:

26 Jan 2018 11:05

Publisher DOI:


PubMed ID:



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