Crooijmans, Hendrikus J. A.; Ruder, Thomas D.; Eggert, Sebastian; Paula, Pia; Thali, Michael J.; Bieri, Oliver; Schweitzer, Wolf (2013). Feasibility of post mortem cardiac proton density weighted fast field echo imaging in two cases of sudden death. Legal medicine, 15(6), pp. 310-314. Elsevier 10.1016/j.legalmed.2013.09.003
Full text not available from this repository. (Request a copy)OBJECTIVE
The aim of this work is to investigate and compare cardiac proton density (PD) weighted fast field echo (FFE) post-mortem magnetic resonance (PMMR) imaging with standard cardiac PMMR imaging (T1-weighted and T2-weighted turbo spin-echo (TSE)), postmortem CT (PMCT) as well as autopsy.
MATERIALS AND METHODS
Two human cadavers sequentially underwent cardiac PMCT and PMMR imaging (PD-weighted FFE, T1-weighted and T2-weighted TSE) and autopsy. The cardiac PMMR images were compared to each other as well as to PMCT and autopsy findings.
RESULTS
For the first case, cardiac PMMR exhibited a focal region of low signal in PD-weighted FFE and T2-weighted TSE images, surrounded by a signal intense rim in the T2-weighted images. T1-weighted TSE and PMCT did not appear to identify any focal abnormality. Macroscopic inspection identified a blood clot; histology confirmed this to be a thrombus with an adhering myocardial infarction. In the second case, a myocardial rupture with heart tamponade was identified in all PMMR images, located at the anterior wall of the left ventricle; PMCT excluded additional ruptures. In PD-weighted FFE and T2-weighted TSE images, it occurred hypo-intense, while resulting in small clustered hyper-intense spots in T1-weighted TSE. Autopsy confirmed the PMMR and PMCT findings.
CONCLUSIONS
Presented initial results have shown PD-weighted FFE to be a valuable imaging sequence in addition to traditional T2-weighted TSE imaging for blood clots and myocardial haemorrhage with clearer contrast between affected and healthy myocardium.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology |
UniBE Contributor: |
Ruder, Thomas |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1344-6223 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Aisha Stefania Mzinga |
Date Deposited: |
13 May 2014 09:53 |
Last Modified: |
05 Dec 2022 14:34 |
Publisher DOI: |
10.1016/j.legalmed.2013.09.003 |
PubMed ID: |
24139838 |
Uncontrolled Keywords: |
Cardiac imaging, Fast field echo, Forensic radiology, Magnetic resonance imaging, Post-mortem magnetic resonance imaging, Virtopsy |
URI: |
https://boris.unibe.ch/id/eprint/52399 |
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