Genetic Control of Plant Development by Overriding a Geometric Division Rule

Yoshida, Saiko; Barbier de Reuille, Pierre; Lane, Brendan; Bassel, George W.; Prusinkiewicz, Przemyslaw; Smith, Richard Simon; Weijers, Dolf (2014). Genetic Control of Plant Development by Overriding a Geometric Division Rule. Developmental cell, 29(1), pp. 75-87. Cell Press 10.1016/j.devcel.2014.02.002

Text barbier_smith.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (4MB)

Formative cell divisions are critical for multicellular patterning. In the early plant embryo, such divisions follow from orienting the division plane. A major unanswered question is how division plane orientation is genetically controlled, and in particular whether this relates to cell geometry. We have generated a complete 4D map of early Arabidopsis embryogenesis and used computational analysis to demonstrate that several divisions follow a rule that uses the smallest wall area going through the center of the cell. In other cases, however, cell division clearly deviates from this rule, which invariably leads to asymmetric cell division. By analyzing mutant embryos and through targeted genetic perturbation, we show that response to the hormone auxin triggers a deviation from the ``shortest wall'' rule. Our work demonstrates that a simple default rule couples division orientation to cell geometry in the embryo and that genetic regulation can create patterns by overriding the default rule.

Interest & Impact

Downloads

6 since deposited on 06 Jun 2014
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item