Leumann, Christian J. (2005). Tuning Molecular Recognition of RNA and DNA via Sugar Modification. CHIMIA, 59(11), pp. 776-779. Bern: Schweizerische Chemische Gesellschaft
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This minireview highlights three aspects of our recent work in the area of sugar modified oligonucleotide analogues. It provides an overview over recent results on the conformationally constrained analogue tricyclo-DNA with special emphasis of its antisense properties, it summarizes results on triple-helix forming oligodeoxynucleotides containing pyrrolidino-nucleosides with respect to DNA recognition via the dual recognition mode, and it highlights the advantageous application of the orthogonal oligonucleotidic pairing system homo-DNA in molecular beacons for DNA diagnostics
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Leumann, Christian |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0009-4293 |
Publisher: |
Schweizerische Chemische Gesellschaft |
Language: |
English |
Submitter: |
Christian Leumann |
Date Deposited: |
26 May 2014 15:28 |
Last Modified: |
05 Dec 2022 14:34 |
Uncontrolled Keywords: |
analogue, analogues, Antisense, DNA, DNA recognition, Homo-DNA, modified, molecular, molecular beacons, molecular recognition, Oligodeoxynucleotides, oligonucleotide, properties, recognition, RNA, sugar, sugar modified, tricyclo-DNA, triple helix |
BORIS DOI: |
10.7892/boris.53107 |
URI: |
https://boris.unibe.ch/id/eprint/53107 |
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