Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors

Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Fani, Melpomeni; Forrer, Flavio; Nicolas, Guillaume; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2011). Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors. Journal of nuclear medicine, 52(12), pp. 1970-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.094375

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Bombesin receptors are overexpressed on a variety of human tumors. In particular, the gastrin-releasing peptide receptor (GRPr) has been identified on prostate and breast cancers and on gastrointestinal stromal tumors. The current study aims at developing clinically translatable bombesin antagonist-based radioligands for SPECT and PET of GRPr-positive tumors.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Cescato, Renzo and Reubi, Jean-Claude

ISSN:

0161-5505

Publisher:

Society of Nuclear Medicine

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

17 Mar 2015 19:23

Publisher DOI:

10.2967/jnumed.111.094375

PubMed ID:

22080443

Web of Science ID:

000298162500034

URI:

https://boris.unibe.ch/id/eprint/5548 (FactScience: 210301)

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