HGF/c-Met related activation of ?-catenin in hepatoblastoma

Purcell, Rachel; Childs, Margaret; Maibach, Rudolf; Miles, Carina; Turner, Clinton; Zimmermann, Arthur; Sullivan, Michael (2011). HGF/c-Met related activation of ?-catenin in hepatoblastoma. Journal of experimental & clinical cancer research, 30, p. 96. Roma: APSIT 10.1186/1756-9966-30-96

Full text not available from this repository. (Request a copy)

Activation of beta-catenin is a hallmark of hepatoblastoma (HB) and appears to play a crucial role in its pathogenesis. While aberrant accumulation of the beta-catenin is a common event in HB, mutations or deletions in CTNNB1 (beta-catenin gene) do not always account for the high frequency of protein expression. In this study we have investigated alternative activation of beta-catenin by HGF/c-Met signaling in a large cohort of 98 HB patients enrolled in the SIOPEL-3 clinical trial.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Zimmermann, Arthur

ISSN:

0392-9078

Publisher:

APSIT

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

17 Mar 2015 19:23

Publisher DOI:

10.1186/1756-9966-30-96

PubMed ID:

21992464

Web of Science ID:

000296516000001

URI:

https://boris.unibe.ch/id/eprint/5600 (FactScience: 210368)

Actions (login required)

Edit item Edit item
Provide Feedback