Purcell, Rachel; Childs, Margaret; Maibach, Rudolf; Miles, Carina; Turner, Clinton; Zimmermann, Arthur; Sullivan, Michael (2011). HGF/c-Met related activation of ?-catenin in hepatoblastoma. Journal of experimental & clinical cancer research, 30(1), p. 96. Roma: APSIT 10.1186/1756-9966-30-96
Full text not available from this repository. (Request a copy)Activation of beta-catenin is a hallmark of hepatoblastoma (HB) and appears to play a crucial role in its pathogenesis. While aberrant accumulation of the beta-catenin is a common event in HB, mutations or deletions in CTNNB1 (beta-catenin gene) do not always account for the high frequency of protein expression. In this study we have investigated alternative activation of beta-catenin by HGF/c-Met signaling in a large cohort of 98 HB patients enrolled in the SIOPEL-3 clinical trial.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Zimmermann, Arthur |
ISSN: |
0392-9078 |
Publisher: |
APSIT |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:18 |
Last Modified: |
05 Dec 2022 14:05 |
Publisher DOI: |
10.1186/1756-9966-30-96 |
PubMed ID: |
21992464 |
Web of Science ID: |
000296516000001 |
URI: |
https://boris.unibe.ch/id/eprint/5600 (FactScience: 210368) |
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