Measuring motor activity in major depression: the association between the Hamilton Depression Rating Scale and actigraphy

Razavi, Nadja; Horn, Helge Joachim; Koschorke, Philipp; Hügli, Simone; Höfle, Oliver; Müller, Thomas Jörg; Strik, Werner; Walther, Sebastian (2011). Measuring motor activity in major depression: the association between the Hamilton Depression Rating Scale and actigraphy. Psychiatry research, 190(2-3), pp. 212-216. Amsterdam: Elsevier 10.1016/j.psychres.2011.05.028

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Despite the use of actigraphy in depression research, the association of depression ratings and quantitative motor activity remains controversial. In addition, the impact of recurring episodes on motor activity is uncertain. In 76 medicated inpatients with major depression (27 with a first episode, 49 with recurrent episodes), continuous wrist actigraphy for 24h and scores on the Hamilton Depression Rating Scale (HAMD) were obtained. In addition, 10 subjects of the sample wore the actigraph over a period of 5 days, in order to assess the reliability of a 1-day measurement. Activity levels were stable over 5 consecutive days. Actigraphic parameters did not differ between patients with a first or a recurrent episode, and quantitative motor activity failed to correlate with the HAMD total score. However, of the motor-related single items of the HAMD, the item activities was associated with motor activity parameters, while the items agitation and retardation were not. Actigraphy is consistent with clinical observation for the item activities. Expert raters may not correctly rate the motor aspects of retardation and agitation in major depression.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > UPD Murtenstrasse
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)

UniBE Contributor:

Razavi, Nadja; Horn, Helge Joachim; Höfle, Oliver; Müller, Thomas Jörg; Strik, Werner and Walther, Sebastian

ISSN:

0165-1781

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

10 Aug 2015 11:21

Publisher DOI:

10.1016/j.psychres.2011.05.028

PubMed ID:

21663976

Web of Science ID:

000298722900009

BORIS DOI:

10.7892/boris.5750

URI:

https://boris.unibe.ch/id/eprint/5750 (FactScience: 210569)

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