Antiretrovirale Therapie

von Braun, Amrei; Furrer, Hansjakob; Battegay, Manuel; Calmy, Alexandra; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Weber, Rainer; Günthard, Huldrych F (2014). Antiretrovirale Therapie. Therapeutische Umschau, 71(8), pp. 461-468. Huber 10.1024/0040-5930/a000538

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Antiretroviral therapy to treat HIV, as we know it today, is nothing less than a huge success story in modern medical history. What used to be an almost certain death-sentence was transformed into a very manageable chronic disease by means of highly efficient und mostly well tolerated drugs. Today, HIV-infected patients treated according to international recommendations have a very good chance to outgo the negative effects of HIV-1 and are therefore able to reach an almost normal life expectancy. Furthermore, patients successfully treated with antiretroviral drugs are no longer infectious, which is an essential aspect of global strategies to overcome the pandemic. Nevertheless, due to the complexity of HIV, physicians treating patients with antiretroviral therapy require profound knowledge of aspects such as viral resistance mechanisms and immune reconstitution, as well as drug-toxicity und drug-drug-interactions. Many other aspects such as long-term side-effects of antiretroviral drugs are still unknown. Strict adherence to treatment is of utmost importance.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Furrer, Hansjakob

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0040-5930

Publisher:

Huber

Language:

German

Submitter:

Annelies Luginbühl

Date Deposited:

14 Oct 2014 11:07

Last Modified:

13 Oct 2017 10:00

Publisher DOI:

10.1024/0040-5930/a000538

PubMed ID:

25093310

BORIS DOI:

10.7892/boris.58159

URI:

https://boris.unibe.ch/id/eprint/58159

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