Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura

Froehlich-Zahnd, Rahel; George, James N; Vesely, Sara K; Terrell, Deirdra R; Aboulfatova, Khatira; Dong, Jing-Fei; Luken, Brenda M; Voorberg, Jan; Budde, Ulrich; Sulzer, Irmela; Lämmle, Bernhard; Kremer Hovinga, Johanna A (2011). Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura. Haematologica - the hematology journal, 97(2), pp. 297-303. Pavia: Ferrata-Storti Foundation

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Severe ADAMTS13 deficiency is a critical component of the pathogenesis of idiopathic thrombotic thrombocytopenic purpura but is found only in about 60% of patients clinically diagnosed with this disease.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Kremer Hovinga, Johanna Anna

ISSN:

0390-6078

Publisher:

Ferrata-Storti Foundation

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

06 Dec 2013 13:26

PubMed ID:

21993669

URI:

https://boris.unibe.ch/id/eprint/5843 (FactScience: 210696)

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