Rapid exclusion or confirmation of heparin-induced thrombocytopenia: a single-center experience with 1,291 patients

Nellen, Vanessa; Sulzer, Irmela; Barizzi, Gabriela; Lämmle, Bernhard; Alberio, Lorenzo (2011). Rapid exclusion or confirmation of heparin-induced thrombocytopenia: a single-center experience with 1,291 patients. Haematologica - the hematology journal, 97(1), pp. 89-97. Pavia: Ferrata-Storti Foundation 10.3324/haematol.2011.048074

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The current gold-standard for diagnosing heparin-induced thrombocytopenia is the detection of platelet-activating antibodies by means of functional assays which, since they are time consuming and not widely available, are not suited to guiding acute treatment decisions. The objective of our study was to assess the ability of more rapid immunoassays to predict the presence of functionally relevant anti-platelet factor 4/heparin-antibodies.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Lämmle, Bernhard and Alberio, Lorenzo

ISSN:

0390-6078

Publisher:

Ferrata-Storti Foundation

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

06 Dec 2013 13:26

Publisher DOI:

10.3324/haematol.2011.048074

PubMed ID:

21933856

Web of Science ID:

000299870500016

URI:

https://boris.unibe.ch/id/eprint/5852 (FactScience: 210705)

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