Hierarchical self-assembly of nucleotide-appended oligopyrenotides into defined supramolecular objects

Vyborna, Yuliia; Vybornyi, Mykhailo; Häner, Robert (11 August 2014). Hierarchical self-assembly of nucleotide-appended oligopyrenotides into defined supramolecular objects. CHIMIA, 68(7-8, Suppl). Bern: Schweizerische Chemische Gesellschaft

[img]
Preview
Text
abstract.pdf - Published Version
Available under License Publisher holds Copyright.

Download (75kB) | Preview

Supramolecular DNA assembly blends DNA building blocks with synthetic organic molecules giving structural and functional advantages. Incorporating extended aromatic molecules as connectors of DNA strands allows folding of these strands through π-π stacking (DNA 'foldamers'). In previous work it was shown that short oligopyrenotides behave as staircase-like foldamers, which cooperatively self-assemble into 2D supramolecular polymers in aqueous medium. Herein, we demonstrate that 10-mer DNA-sequence conjugated with seven pyrene unites forms dimensionally-defined supramolecular polymers under thermodynamic conditions in water. We present the self-assembly behavior, morphologycal studies (AFM and TEM), and the spectroscopic properties (UV/vis, CD) of the investigated pyrene - conjugated DNA-sequence.

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Vyborna, Yuliia; Vybornyi, Mykhailo and Häner, Robert

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

0009-4293

Publisher:

Schweizerische Chemische Gesellschaft

Language:

English

Submitter:

Yuliia Vyborna

Date Deposited:

06 Oct 2014 11:19

Last Modified:

26 Apr 2017 02:29

BORIS DOI:

10.7892/boris.58925

URI:

https://boris.unibe.ch/id/eprint/58925

Actions (login required)

Edit item Edit item
Provide Feedback