The Role of the Right Posterior Parietal Cortex in Letter Migration between Words

Cazzoli, Dario; Müri, René Martin; Kennard, Christopher; Rosenthal, Clive R (2015). The Role of the Right Posterior Parietal Cortex in Letter Migration between Words. Journal of cognitive neuroscience, 27(2), pp. 377-386. MIT Press Journals 10.1162/jocn_a_00713

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When briefly presented with pairs of words, skilled readers can sometimes report words with migrated letters (e.g., they report hunt when presented with the words hint and hurt). These letter migration phenomena have been often used to investigate factors that influence reading such as letter position coding. However, the neural basis of letter migration is poorly understood. Previous evidence has implicated the right posterior parietal cortex (PPC) in processing visuospatial attributes and lexical properties during word reading. The aim of this study was to assess this putative role by combining an inhibitory TMS protocol with a letter migration paradigm, which was designed to examine the contributions of visuospatial attributes and lexical factors. Temporary interference with the right PPC led to three specific effects on letter migration. First, the number of letter migrations was significantly increased only in the group with active stimulation (vs. a sham stimulation group or a control group without stimulation), and there was no significant effect on other error types. Second, this effect occurred only when letter migration could result in a meaningful word (migration vs. control context). Third, the effect of active stimulation on the number of letter migrations was lateralized to target words presented on the left. Our study thus demonstrates that the right PPC plays a specific and causal role in the phenomenon of letter migration. The nature of this role cannot be explained solely in terms of visuospatial attention, rather it involves an interplay between visuospatial attentional and word reading-specific factors.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Cazzoli, Dario and Müri, René Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0898-929X

Publisher:

MIT Press Journals

Language:

English

Submitter:

Valentina Rossetti

Date Deposited:

14 Oct 2014 07:48

Last Modified:

18 Feb 2015 12:05

Publisher DOI:

10.1162/jocn_a_00713

PubMed ID:

25203274

URI:

https://boris.unibe.ch/id/eprint/59085

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